Allosteric control of a DNA-hydrolyzing deoxyribozyme with short oligonucleotides and its application in DNA logic gates.
نویسندگان
چکیده
Allosteric control of deoxyribozymes is useful for a broad range of practical applications, such as nucleic acid sensing and DNA-computing. We found that the catalytic activity of a DNA-hydrolyzing deoxyribozyme could be allosterically regulated by adding short oligonucleotides. We used this technique to construct deoxyribozyme-based logic gates.
منابع مشابه
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 21 شماره
صفحات -
تاریخ انتشار 2014